Little was detailed about Vulture’s life before the zombie plague arrived on Earth-2149, however it appears to have been somewhat different from his Earth-616 counterpart, as his allegiance to zombified heroes indicates he may have been a superhero in this world rather than a villain. 

Infected at some point, Vulture was one of the zombie members of the Sinister Six who battled Wolverine and Magneto as they aided various people in taking shelter on a S.H.I.E.L.D. Helicarrier. Vulture later joined the assembled zombified heroes in attacking the Silver Surfer in New York, where he was injured with a cosmic blast but not killed.

When Machine Man and Jocasta arrived in New York Central Park on Earth-2149, they were attacked by the zombified Vulture, Beak, Falcon and Angel. Machine Man made short work of them and dispatched them all with glee. Vulture, however, was the only one that survived and escaped.