Aaron Aikman was a scientist working for the Ikegami Medical Center, specializing in the medical application of insect venoms. When he was twenty, Hannah, the daughter of his boss Kaori Ikegami, was critically injured after being hit by a car and he volunteered his services to help her recover. Eventually, he and Kaori became romantically involved.

When he was twenty-four, Aaron secretly underwent an experimental treatment that resequenced his DNA with that of a genetically-altered spider, developing superhuman abilities. Building a suit of cybernetic armor to augment his powers, Aaron became the Spider-Man to combat the super villain Redeye.