She starred as Sandy in a high school production of the musical Grease. She did a YouTube collaboration video with Sofie Dossi early in 2019.
Pansino began her YouTube channel in 2009 after she was encouraged by a few of her friends who had also worked on YouTube, and had started making videos to get more comfortable in front of a camera.
Creator of the hit YouTube baking show Nerdy Nummies who signed with Kin Community, one of the top multi-channel networks for women on YouTube.
Pansino has hosted the internet series Nerdy Nummies since 2011, which won her a Shorty Award and earned her five Streamy Award nominations.